化工社化工社 化学情報印刷レポート · 研究参考用
Triethylamine → Ethyl N-(4-methyl-2-oxazolyl)carbamate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Ethyl chloroformate | HCID 10928 | — |
| 反応物 | 4-Methyloxazol-2-amine | HCID 535824 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | Ethyl N-(4-methyl-2-oxazolyl)carbamate | HCID 23468960 | — |
反応手順
Ethyl chloroformate (1.05 ml, 0.011 mol) was added dropwise to a stirred solution of 2-amino-4-methyloxazole (1.0 g, 0.010 mol) and triethylamine (1.5 ml, 0.011 mol) in dry ether (50 ml) at 5°-10° C. The mixture was stirred for 2 hours at 0°-5° C. then the white solid was filtered off and washed well with water to remove triethylamine hydrochloride. Residue (0.5 g) was recrystallised from chloroform-petroleum spirit, m.p. 126° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04175131 |
| 出典データセット | uspto-grants-1979_11 |
| ORD ID | ord-293f27be2e06490ea50a569219038416 |
| 出典メモ | uspto-grants-1979_11 |