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2-(4-amino-2-butyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)ethaneamine → HCID 178441566、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(4-amino-2-butyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)ethaneamine | HCID 21946027 | — |
| 反応物 | HCID 178524392 | HCID 178524392 | — |
| 生成物 | HCID 178441566 | HCID 178441566 | 21.8% |
反応手順
Using the general method of Example 97 6-hydroxypicolinic acid (0.24 g, 1.7 mmole) was reacted with 2-(4-amino-2-butyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)ethaneamine (0.5 g, 1.7 mmol) to provide 0.15 g of N-[2-(4-amino-2-butyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)ethyl]-6-hydroxy-2-pyridinecarboxamide as a white powder, m.p. 258-260° C. Analysis: Calculated for C21H23N7O2+½ CH3CN: %C, 62.03; %H, 5.80; %N, 24.66. Found: %C, 61.87; %H, 5.70; %N, 24.60.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06699878B2 |
| 出典データセット | uspto-grants-2004_03 |
| ORD ID | ord-e9083d2ce62d487684022ded273cd3d7 |
| 出典メモ | uspto-grants-2004_03 |