関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 6-Methyluracil | HCID 12283 | — |
| 反応物 | Phosphorus sulfide (P2S5) | HCID 14817 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | HCID 178429729 | HCID 178429729 | 136.5% |
反応手順
6-Methyluracil (25.0 g) was suspended in 1 liter of distilled pyridine with stirring and heated at 50° C. into solution. Phosphorus pentasulfide (12.6 g) was then added, and the mixture was refluxed for 20 hours. The solution was concentrated under reduced pressure, then the residue was refluxed with 500 ml of ethanol for one hour. Insoluble materials were removed by filtration and the filtrate was concentrated under reduced pressure. The residue was recrystallized from ethanol, affording 5.5 g of the objective compound as colorless crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04888332 |
|---|
| 出典データセット | uspto-grants-1989_12 |
|---|
| ORD ID | ord-8803435dd1da4637b5700b006de1fda9 |
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| 出典メモ | uspto-grants-1989_12 |
|---|
