化工社化工社 化学情報印刷レポート · 研究参考用
Sodium → 5-Methyl-6-oxoheptanesulfonic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium | HCID 5360545 | — |
| 反応物 | 5-(Ethoxycarbonyl)-5-methyl-6-oxoheptane-1-sulphonate | HCID 59422465 | — |
| 溶媒 | Hydrochloric Acid | HCID 313 | — |
| 生成物 | 5-Methyl-6-oxoheptanesulfonic acid | HCID 57903351 | — |
反応手順
5-(Ethoxycarbonyl)-5-methyl-6-oxoheptane-1-sulphonate, sodium salt (from 1.1) was heated at 90° C. in concentrated hydrochloric acid (200 ml), until TLC indicated complete reaction (˜3 hrs). The solvent was then evaporated under vacuum; the residue was purified by flash chromatography (Silica. Ethanol/dichloromethane mixtures) to give 49.6 g of 5-methyl-6-oxoheptane-1-sulphonic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07767829B2 |
| 出典データセット | uspto-grants-2010_08 |
| ORD ID | ord-d343bf7b98de416fb47c01395140dd59 |
| 出典メモ | uspto-grants-2010_08 |