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Hydrazine, [4-[(trifluoromethyl)thio]phenyl]- → HCID 58731518、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrazine, [4-[(trifluoromethyl)thio]phenyl]- | HCID 10420564 | — |
| 反応物 | 5-Methyl-6-oxoheptanesulfonic acid | HCID 57903351 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | HCID 58731518 | HCID 58731518 | 14.2% |
反応手順
To 4-(trifluoromethylthio)phenylhydrazine (1 g) in acetic acid (40 ml) was added 5-methyl-6-oxoheptane-1-sulphonic acid (1.4 g) and the solution heated to reflux overnight. The volatiles were removed on a rotary evaporator to give the crude product, 1.1 g of which was purified by preparative HPLC. The relevant fractions were combined, concentrated on a rotary evaporator and freeze dried to give the desired product (260 mg). M+=381
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07767829B2 |
| 出典データセット | uspto-grants-2010_08 |
| ORD ID | ord-7773518b75a34179bcb983a4bc6863e6 |
| 出典メモ | uspto-grants-2010_08 |