化工社化工社 化学情報印刷レポート · 研究参考用
1-Mercapto-2-propanol → N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-4-(2-hydroxypropylthio)butyramide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Mercapto-2-propanol | HCID 102545 | — |
| 反応物 | N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-4-chlorobutyramide | HCID 67726214 | — |
| 生成物 | N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-4-(2-hydroxypropylthio)butyramide | HCID 67726334 | 58% |
反応手順
Following a procedure similar to that described in Example 1, but using N-[4-(4-piperidinomethyl-2-pyridyloxy) -cis-2-butenyl]-4-chlorobutyramide (prepared as described in Preparation 2) and 1-mercapto-2-propanol as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a 58% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05616579 |
| 出典データセット | uspto-grants-1997_04 |
| ORD ID | ord-43ec493ff4d44903a0e5cba4aa27465f |
| 出典メモ | uspto-grants-1997_04 |