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1-Methyl-2-pyrrolecarboxylic acid → 1-Methyl-N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]pyrrole-2-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Methyl-2-pyrrolecarboxylic acid | HCID 81453 | — |
| 反応物 | 2-Buten-1-amine, 4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-, (Z)- | HCID 13672473 | — |
| 生成物 | 1-Methyl-N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]pyrrole-2-carboxamide | HCID 67725801 | 76% |
反応手順
Following a procedure similar to that described in Example 13, but using 4-(4-piperidinomethyl-2-pyridyloxy) -cis-2-butenylamine and 1-methyl-2-pyrrolecarboxylic acid as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as an oil in a 76% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05616579 |
| 出典データセット | uspto-grants-1997_04 |
| ORD ID | ord-1fd8c49b226148c6893cd1cb818eb079 |
| 出典メモ | uspto-grants-1997_04 |