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1H-Indazol-6-amine → N2,N4-bis(6-indazolyl)-5-ethoxycarbonyl-2,4-primidinediamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1H-Indazol-6-amine | HCID 81423 | — |
| 反応物 | Ethyl 2,4-dichloropyrimidine-5-carboxylate | HCID 104020 | — |
| 生成物 | N2,N4-bis(6-indazolyl)-5-ethoxycarbonyl-2,4-primidinediamine | HCID 22060443 | — |
反応手順
In like manner to N2,N4-bis(3-hydroxyphenyl)-5-ethoxycarbonyl-2,4-pyrimidinediamine, 2,4-dichloro-5-ethoxycarbonylpyrimidine and 6-aminoindazole were reacted to yield N2,N4-bis(6-indazolyl)-5-ethoxycarbonyl-2,4-pyrimidinediamine. 1H NMR (DMSO-d6): δ 8.76 (s, 1H), 7.73 (d, 2H J=8.8), 7.54 (m, 4H), 7.36 (d, 2H, J=9.5 Hz), 4.3 (q, 2H, J=7.0 Hz), 1.34 (3H, J=7 Hz); LCMS: ret. time 27.59 min.; purity: 95%; MS (m/e): 415 (MH+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09346765B2 |
| 出典データセット | uspto-grants-2016_05 |
| ORD ID | ord-4f4f6c3d25fd44219cd07b077dea060c |
| 出典メモ | uspto-grants-2016_05 |