化工社化工社 化学情報印刷レポート · 研究参考用
1,7-Diphenyl-4-heptanol → 1-(4-tert-Butyldiphenylsilyloxymethylphenyl)-7-phenyl-heptan-4-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,7-Diphenyl-4-heptanol | HCID 10539870 | — |
| 反応物 | 4-(4-tert-Butyldiphenylsilyloxymethyl-phenyl)butyraldehyde | HCID 19694131 | — |
| 反応物 | HCID 178418471 | HCID 178418471 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 1-(4-tert-Butyldiphenylsilyloxymethylphenyl)-7-phenyl-heptan-4-ol | HCID 19694136 | 122.9% |
反応手順
The alcohol 173 was prepared from 2.12 g (5.0 mmol) of 172 and 9.0 mL (9 mmol) of 120 in 50 mL of THF as described for the synthesis of 121 in Example 1. Flash chromatography (elution with 10% ethyl acetate in hexane) gave 3.3 g of the alcohol 173. 1H NMR consistent with the product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05620971 |
| 出典データセット | uspto-grants-1997_04 |
| ORD ID | ord-f6cec43e01da4b7f9c141f242587d7b6 |
| 出典メモ | uspto-grants-1997_04 |