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Iodine → 2-Benzyl-6-phenyl-isothiazolo[5,4-d]pyrimidin-3-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Iodine | HCID 807 | — |
| 反応物 | HCID 178418303 | HCID 178418303 | — |
| 生成物 | 2-Benzyl-6-phenyl-isothiazolo[5,4-d]pyrimidin-3-one | HCID 23287902 | 87.6% |
反応手順
Using the procedure of Example 20, 2.0 g (6.22 mmol) of 4-mercapto-2-phenyl-pyrimidine-5-carboxylic acid benzylamide (from Preparation 42) was reacted with 1.74 g (6.8 mmol) of iodine to give 1.74 g of the title compound after crystallization from isopropanol, mp 166°-167° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05620997 |
| 出典データセット | uspto-grants-1997_04 |
| ORD ID | ord-b44c82636d854ec29f3c95413e79d974 |
| 出典メモ | uspto-grants-1997_04 |