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Dimethyl Sulfoxide → 1-(4-Chlorophenyl)-cyclopentanecarbaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethyl Sulfoxide | HCID 679 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 反応物 | 1-(p-Chlorophenyl)cyclopentanemethanol | HCID 2724017 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 1-(4-Chlorophenyl)-cyclopentanecarbaldehyde | HCID 21468000 | — |
反応手順
This compound is prepared in a manner analogous to that of Step B of Example 4, using 7.0 grams (0.055 mole) of oxalyl chloride, 9.5 grams (0.120 mole) of dimethyl sulfoxide, 10.5 grams (0.050 mole) of [1-(4-chlorophenyl)-1-cyclopentyl]methanol, and 25.5 grams (0.250 mole) of triethylamine in 175 mL of methylene chloride, yielding 1-(4-chlorophenyl)-1-cyclopentanecarboxaldehyde.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05622954 |
| 出典データセット | uspto-grants-1997_04 |
| ORD ID | ord-77961596412b4d11bac1cca180d2c59a |
| 出典メモ | uspto-grants-1997_04 |