化工社化工社 化学情報印刷レポート · 研究参考用
Water → 2-(3-Nitrobenzylidene)-3,4-dihydronaphthalen-1(2h)-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 3-Nitrobenzaldehyde | HCID 7449 | — |
| 反応物 | 1-Tetralone | HCID 10724 | — |
| 反応物 | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 2-(3-Nitrobenzylidene)-3,4-dihydronaphthalen-1(2h)-one | HCID 288804 | — |
反応手順
A mixture of 3,4-dihydro-1(2H)-naphthalenone (21.9 g), 3-nitrobenzaldehyde (22.6 g) and p-toluenesulphonic acid monohydrate (50 mg) in toluene (250 ml) was stirred at reflux with separation of water for 4.5 hours. The brown solution was allowed to cool overnight. The resulting yellow-orange deposited solid was filtered off, washed well with toluene and dried in vacuo yielding 2-(3-nitrobenzylidene)-3,4-dihydro-1(2H)-naphthalenone as crisp yellow needles.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05622987 |
| 出典データセット | uspto-grants-1997_04 |
| ORD ID | ord-24bd5505bcae4988aed129c6132f0ea9 |
| 出典メモ | uspto-grants-1997_04 |