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1-(Bromomethyl)-4-(trifluoromethyl)benzene → HCID 58031402、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(Bromomethyl)-4-(trifluoromethyl)benzene | HCID 123062 | — |
| 反応物 | 8-(Bromomethyl)quinoline | HCID 346914 | — |
| 反応物 | Ethyl 4-methyl-2-(2-oxoimidazolidin-1-yl)thiazole-5-carboxylate | HCID 57919776 | — |
| 生成物 | HCID 58031402 | HCID 58031402 | 82% |
反応手順
Following the procedure as described in Example 13, making variations as required to replace 4-(trifluoromethyl)benzyl bromide with 8-(bromomethyl)quinoline to react with ethyl 4-methyl-2-(2-oxoimidazolidin-1-yl)thiazole-5-carboxylate, the title compound was obtained as a colorless solid in 82% yield: MS (ES+) m/z 397.3 (M+1)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08063084B2 |
| 出典データセット | uspto-grants-2011_11 |
| ORD ID | ord-bf5e068c7ad54edfa8e1307d9c90608b |
| 出典メモ | uspto-grants-2011_11 |