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1-(4-Fluorophenyl)-2-(piperazin-1-yl)ethan-1-one dihydrochloride → HCID 178521227、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(4-Fluorophenyl)-2-(piperazin-1-yl)ethan-1-one dihydrochloride | HCID 42933716 | — |
| 反応物 | HCID 178524948 | HCID 178524948 | — |
| 生成物 | HCID 178521227 | HCID 178521227 | 65.3% |
反応手順
The title compound was prepared in a similar manner as described in Example 1.2, using 4-chloro-1H-pyrazole-3-carboxylic acid (22.0 mg), and 1-(4-fluorophenyl)-2-(piperazin-1-yl)ethanone dihydrochloride (29.5 mg) as starting materials, to afford the title compound (22.9 mg) as a white solid. Exact mass calculated for C16H16ClFN4O2: 350.1. Found: LCMS m/z (%)=351.3 (M+H+35Cl, 100%), 353.3 (M+H+37Cl, 32%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09434692B2 |
| 出典データセット | uspto-grants-2016_09 |
| ORD ID | ord-a3055e906fc847649f9027cead46efa8 |
| 出典メモ | uspto-grants-2016_09 |