化工社化工社 化学情報印刷レポート · 研究参考用
Guanidine Hydrochloride → HCID 178478910、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Guanidine Hydrochloride | HCID 5742 | — |
| 反応物 | Methyl 1-methyl-1H-indole-5-carboxylate | HCID 10679201 | — |
| 反応物 | Sodium Methoxide | HCID 10942334 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | HCID 178478910 | HCID 178478910 | 68.9% |
反応手順
The reaction was carried out in a manner similar to Example 1 except for using 1.00 g (5.29 mmol) of methyl 1-methyl-5-indolecarboxylate, 5.05 g (52.9 mmol) of guanidine hydrochloride and 50 ml of a methanol solution of 2.85 g (52.9 mmol) of sodium methoxide. Thus 0.92 g (68.9%) of 1-methyl-5-indoloylguanidine hydrochloride was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06169107A |
| 出典データセット | uspto-grants-2001_01 |
| ORD ID | ord-79b75a0701a94757837a47f7f0a1043e |
| 出典メモ | uspto-grants-2001_01 |