化工社化工社 化学情報印刷レポート · 研究参考用
Formaldehyde → L-Pantothenic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Formaldehyde | HCID 712 | — |
| 反応物 | (+-)-Pantolactone | HCID 989 | — |
| 反応物 | Cyanide | HCID 5975 | — |
| 反応物 | Isobutyraldehyde | HCID 6561 | — |
| 反応物 | Pantothenic Acid | HCID 6613 | — |
| 生成物 | L-Pantothenic acid | HCID 5748353 | — |
反応手順
Pantothenic acid can be prepared by chemical synthesis, or biotechnologically by the fermentation of suitable microorganisms in suitable nutrient solutions. In the chemical synthesis, DL-pantolactone is an important compound. It is prepared in a multi-stage process from formaldehyde, isobutyraldehyde and cyanide. In further process steps, the racemic mixture is separated, D-pantolactone is subjected to a condensation reaction with β-alanine, and D-pantothenic acid is obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06171845B2 |
| 出典データセット | uspto-grants-2001_01 |
| ORD ID | ord-f43f0c8e4a324914a5e057090eee669e |
| 出典メモ | uspto-grants-2001_01 |