化工社化工社 化学情報印刷レポート · 研究参考用
Benzoic acid, 4-amino-, 1,1-dimethylethyl ester → Tert-butyl 4-(2-(4-(2,5-dichlorophenyl)-2-oxopyridin-1(2h)-yl)propanamido)benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzoic acid, 4-amino-, 1,1-dimethylethyl ester | HCID 233272 | — |
| 反応物 | 2-[4-(2,5-Dichlorophenyl)-2-oxopyridin-1(2H)-yl]propanoic acid | HCID 117622564 | — |
| 生成物 | Tert-butyl 4-(2-(4-(2,5-dichlorophenyl)-2-oxopyridin-1(2h)-yl)propanamido)benzoate | HCID 117622667 | — |
反応手順
117 mg (0.36 mmol) of 2-[4-(2,5-dichlorophenyl)-2-oxopyridin-1(2H)-yl]propanoic acid (racemate) and 1.2 eq. of tert-butyl 4-aminobenzoate were reacted according to General Method 5A. Yield: 83 mg (47% of theory)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09434690B2 |
| 出典データセット | uspto-grants-2016_09 |
| ORD ID | ord-7a827b9686aa4e8e877af8c33ecb9ff5 |
| 出典メモ | uspto-grants-2016_09 |