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2,3,4-tri-O-acetyl-5-thio-alpha-xylopyranosyl bromide → 2-cyanophenyl 2,3,4-tri-O-acetyl-1,5-dithio-beta-D-xylopyranoside
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,3,4-tri-O-acetyl-5-thio-alpha-xylopyranosyl bromide | HCID 10926314 | — |
| 反応物 | 2-Mercaptobenzonitrile | HCID 11018926 | — |
| 触媒 | Zinc Oxide | HCID 3007857 | — |
| 生成物 | 2-cyanophenyl 2,3,4-tri-O-acetyl-1,5-dithio-beta-D-xylopyranoside | HCID 14795345 | 60% |
反応手順
If the procedure described in Preparation IV is followed starting from 10.7 g (79.2.10-3 mol) of 2-mercaptobenzonitrile, 30.2 g (85.10-3 mol) of 2,3,4-tri-O-acetyl-5-thio-α-D-xylopyranosyl bromide and 6.3 g (77.4.10-3 mol) of zinc oxide (ZnO), 19.3 g (yield: 60%) of the expected product are obtained after crystallization from ether.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05246961 |
| 出典データセット | uspto-grants-1993_09 |
| ORD ID | ord-021666c894ee4cbba7a64470dd7059e7 |
| 出典メモ | uspto-grants-1993_09 |