化工社化工社 化学情報印刷レポート · 研究参考用
HRID 601264作成日：2026年10月24日
3-Methylcyclohexanone → 6-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-7-hydroxy-4-{[3-methylcyclohexylidene]amino}thieno[3,2-b]pyridin-5(4H)-one
https://huagongshe.com/ja/reaction/601264
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 3-Methylcyclohexanone | HCID 11567 | — |
| 反応物 | 4-amino-6-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-7-hydroxythieno[3,2-b]pyridin-5(4H)-one | HCID 136373627 | — |
| 溶媒 | Dimethylacetamide | HCID 31374 | — |
| 生成物 | 6-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-7-hydroxy-4-{[3-methylcyclohexylidene]amino}thieno[3,2-b]pyridin-5(4H)-one | HCID 136358481 | — |
反応手順
The product of Example 268D (0.054 g, 0.15 mmol) was reacted with 3-methylcyclohexanone (1.26 g, 11.25 mmol) in N,N-dimethylacetamide (1 mL) in a sealed tube at 135° C. for 45 minutes in a microwave reactor. The reaction was cooled to 25° C. and concentrated under vacuum. The resulting residue was triturated with diethyl ether (3 mL) and filtered to give the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US07902203B2 |
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| 出典データセット | uspto-grants-2011_03 |
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| ORD ID | ord-e4632e7690844eb6b4e6e8f796767630 |
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| 出典メモ | uspto-grants-2011_03 |
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