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Resorcinol → 2-Ethyl-4-(3-trifluoromethylphenyl)-7-hydroxy-2-methyl-2H-chromene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Resorcinol | HCID 5054 | — |
| 反応物 | Boron trifluoride etherate | HCID 8000 | — |
| 反応物 | Chromanone | HCID 68110 | — |
| 反応物 | 2-Ethyl-7-hydroxy-2-methyl-4-chromanone | HCID 20570508 | — |
| 反応物 | HCID 178506173 | HCID 178506173 | — |
| 生成物 | 2-Ethyl-4-(3-trifluoromethylphenyl)-7-hydroxy-2-methyl-2H-chromene | HCID 20570565 | — |
反応手順
2-Ethyl-7-hydroxy-2-methyl-4-chromanone, m.p. 109°-110.5° C., was prepared by condensing resorcinol with 3-methyl-2-pentanoic acid in the presence of boron trifluoride diethyl etherate. Reaction of the chromanone with 3-trifluoromethylphenyl magnesium bromide as described in Preparation 5 gave the title chromene as a golden yellow oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04146539 |
| 出典データセット | uspto-grants-1979_03 |
| ORD ID | ord-5bd9a4ba3af041a393e3f50f4cf9bc71 |
| 出典メモ | uspto-grants-1979_03 |