関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 4-tert-Butylcyclohexylamine | HCID 79396 | — |
| 反応物 | 9,10-Dioxo-9,10-dihydro-anthracene-2,7-disulfonyl dichloride | HCID 23436603 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | N2,N7-bis(4-tert-butylcyclohexyl)-9,10-dioxo-9,10-dihydroanthracene-2,7-disulfonamide | HCID 46851178 | 95% |
反応手順
Anthraquinone-2,7-disulfonylchloride (10 g, 24.7 mmol)) was dissolved in 200 mL DCM. The solution was cooled to −50° C. To this solution was added 4-tert-butylcyclohexanamine (8.43 g, 54 mmol), followed by triethyl amine (8.6 ml, 61.7 mmol). The reaction mixture was stirred at room temperature for 4 hrs. Solvent was evaporated and the residue was treated with MeOH, filtered off, and dried to obtain 15 g (95%) of the product (1-36) as yellow powder.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US09446021B2 |
|---|
| 出典データセット | uspto-grants-2016_09 |
|---|
| ORD ID | ord-e94f88dfad7944568fb1165923aa7c7f |
|---|
| 出典メモ | uspto-grants-2016_09 |
|---|
