化工社化工社 化学情報印刷レポート · 研究参考用
Azobisisobutyronitrile → Chrysanthemic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Azobisisobutyronitrile | HCID 6547 | — |
| 反応物 | Chrysanthemic acid, cis-(-)- | HCID 20755 | — |
| 反応物 | Bromine | HCID 24408 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 溶媒 | Carbon Tetrachloride | HCID 5943 | — |
| 生成物 | Chrysanthemic Acid | HCID 2743 | 90.4% |
反応手順
500 mg of (-)-cis-chrysanthemic acid was dissolved in 10 ml of toluene, followed by adding 20 mg of azobisisobutyronitrile. Thereto was added dropwise a solution of bromine (19 mg) in carbon tetrachloride at 80° C. over a period of 10 minutes with stirring. After 15 minutes, the reaction mixture was subjected to a treatment similar to Example 1 to obtain 452 mg of chrysanthemic acid. The optical isomer ratio was as follows: (+)-cis, 3.3%; (-)-cis, 3.2%; (+)-trans, 47.0%; and (-)-trans, 46.5%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04820864 |
| 出典データセット | uspto-grants-1989_04 |
| ORD ID | ord-8f2f56d3eeb5432896c518c1e5fd3ef8 |
| 出典メモ | uspto-grants-1989_04 |