関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | 3-Nitrophenol | HCID 11137 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Tetradecanoic acid, 2-bromo-, ethyl ester | HCID 85791 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Ethyl 2-(3-nitrophenoxy)tetradecanoate | HCID 14122414 | — |
反応手順
A mixture of 250 g (1.79 mol) of m-nitrophenol, 602 g (1.79 mol) of Alphabromo-myristic acid ethyl ester, 248 g (1.79 mol) of potassium carbonate, and 1350 ml of dimethylformamide is heated to 80° C. for 3 h with stirring. The mixture is then poured out slowly into a mixture of 2300 ml of water and 250 ml of acetic acid. The product is extracted with dichloromethane. The solvent is removed by evaporation.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04822729 |
|---|
| 出典データセット | uspto-grants-1989_04 |
|---|
| ORD ID | ord-8e1268a3ad914c10b3412d4df8d51779 |
|---|
| 出典メモ | uspto-grants-1989_04 |
|---|
