化工社化工社 化学情報印刷レポート · 研究参考用
p-Toluenesulfonic acid → 2-(Chloroethyl)-3-methyl-5,6-dihydro-1,4-dithiin
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | p-Toluenesulfonic acid | HCID 6101 | — |
| 反応物 | 1,1-Ethanedithiol | HCID 33645 | — |
| 反応物 | 3,5-Dichloropentan-2-one | HCID 94032 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 2-(Chloroethyl)-3-methyl-5,6-dihydro-1,4-dithiin | HCID 14551710 | 32% |
反応手順
A mixture of 0.1 mole (15.4 g.) 3,5-dichloro-2-pentanone, 0.1 mole (9.4 g.) ethanedithiol and 0.3 mole PTSA was stirred at room temperature overnight. The product was taken up in toluene, washed with 5% sodium bicarbonate and water, dried over magnesium sulfate, filtered and the solvent removed. The product was distilled; bp. 114°-116°/0.7 mm. Yield 32%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04822813 |
| 出典データセット | uspto-grants-1989_04 |
| ORD ID | ord-6f50d090d94348cfbe37538b26c65891 |
| 出典メモ | uspto-grants-1989_04 |