化工社化工社 化学情報印刷レポート · 研究参考用
4-Methoxymethyl-oxazole → [2-Amino-6-(4-methoxymethyl-oxazol-2-yl)-3-nitro-pyridin-4-yl]-(6-methyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Methoxymethyl-oxazole | HCID 23080903 | — |
| 反応物 | (2-Amino-6-bromo-3-nitro-pyridin-4-yl)-(6-methyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester | HCID 86614483 | — |
| 触媒 | Bis(triphenylphosphine)palladium chloride | HCID 84124 | — |
| 生成物 | [2-Amino-6-(4-methoxymethyl-oxazol-2-yl)-3-nitro-pyridin-4-yl]-(6-methyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester | HCID 67456273 | — |
反応手順
The title compound was prepared following the example in preparation 70, using 4-methoxymethyl-oxazole (110 mg), (2-amino-6-bromo-3-nitro-pyridin-4-yl)-(6-methyl-pyridin-3-ylmethyl)-carbamic acid ethyl ester (200 mg) and palladium bis(triphenylphosphine)dichloride (68 mg), giving the product (107 mg) as a yellow gum.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07691877B2 |
| 出典データセット | uspto-grants-2010_04 |
| ORD ID | ord-9ac59115ac0b469fae32f8dda97f4651 |
| 出典メモ | uspto-grants-2010_04 |