化工社化工社 化学情報印刷レポート · 研究参考用
Dextroamphetamine → Lisdexamfetamine Dimesylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dextroamphetamine | HCID 5826 | — |
| 反応物 | Amphedrine | HCID 222898 | — |
| 反応物 | L-lysine d-amphetamine | HCID 131727865 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Lisdexamfetamine Dimesylate | HCID 11597697 | — |
反応手順
Male Sprague-Dawley rats were provided water ad libitum, fasted overnight, and dosed by oral gavage with 1.5, 3, 6, 12, and 60 mg/kg of amphetamine sulfate or L-lysine-d-amphetamine containing the equivalent amounts of d-amphetamine. Concentrations of d-amphetamine were measured by ELISA.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07700561B2 |
| 出典データセット | uspto-grants-2010_04 |
| ORD ID | ord-e49b75f9167f4493828b512bab7809bf |
| 出典メモ | uspto-grants-2010_04 |