関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dl-Phenylalanine | HCID 994 | — |
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | N-benzenesulfonyl-L-aspartic acid | HCID 10989413 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | L-phenylalanine N-benzenesulfonyl-L-aspartic acid | HCID 86740983 | 35.8% |
反応手順
Six grams of DL-phenylalanine, 5.4 g of N-benzenesulfonyl-L-aspartic acid and 1.8 g of sulfuric acid were dissolved in 110 ml of water. While this solution was continuously stirred at 50° C., a 10% aqueous solution of caustic soda (7.3 ml) was added over five hours. The resulting crystal was separated, washed with 10 ml of water and dried to give 3.1 g of an L-phenylalanine/N-benzenesulfonyl-L-aspartic acid salt. Analysis of this salt revealed that the optical purity of the L-phenylalanine was 94%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US04610827 |
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| 出典データセット | uspto-grants-1986_09 |
|---|
| ORD ID | ord-c087e91160fd4e2da6eb826b5be34b36 |
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| 出典メモ | uspto-grants-1986_09 |
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