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Allyl bromide → 5-Allyloxy-2-methylthiopyrimidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Allyl bromide | HCID 7841 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 2-(Methylsulfanyl)pyrimidin-5-ol | HCID 588357 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | 5-Allyloxy-2-methylthiopyrimidine | HCID 20483481 | — |
反応手順
4.5 g of 5-hydroxy-2-methylthiopyrimidine, 9.0 g of potassium carbonate and 3.9 g of allyl bromide are together refluxed in 50 ml of acetone, with stirring, for 41/2 hours. The inorganic salts are removed by filtration, and the filtrate is concentrated under reduced pressure. The oil remaining yields, from petroleum ether, 5-allyloxy-2-methylthiopyrimidine, m.p. 41°-42°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04410530 |
| 出典データセット | uspto-grants-1983_10 |
| ORD ID | ord-22464af4a91e4835a364c5380e760b20 |
| 出典メモ | uspto-grants-1983_10 |