化工社化工社 化学情報印刷レポート · 研究参考用
Carbon Disulfide → n-Decyl (3S)-3-hydroxymethyl-1,2,3,4-tetrahydro-beta-carboline-2-carbodithioate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Carbon Disulfide | HCID 6348 | — |
| 反応物 | 1-Bromodecane | HCID 8173 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | (3S)-3-hydroxymethyl-1,2,3,4-tetrahydro-beta-carboline | HCID 13375506 | — |
| 溶媒 | Dimethyl Sulfoxide | HCID 679 | — |
| 生成物 | n-Decyl (3S)-3-hydroxymethyl-1,2,3,4-tetrahydro-beta-carboline-2-carbodithioate | HCID 13392983 | — |
反応手順
In the same manner as described in Example 29 by using (3S)-3-hydroxymethyl-1,2,3,4-tetrahydro-β-carboline (2.02 g), triethylamine (1.67 ml), CS2 (0.72 ml), n-decyl bromide (2.65 g) and dimethylsulfoxide (10 ml), there is prepared the title compound (2,48 g, 59%) as colorless needles, m.p. 115°-118° C. (recrystallized from ether-n-hexane), [α]D20 +113.0° (c=1.0, methanol); NMR (CDCl3, δ): 0.95 (m, 3H, --CH3); Mass m/e: 418 (M+), 244 (M+ --C10H21SH).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04612317 |
| 出典データセット | uspto-grants-1986_09 |
| ORD ID | ord-fe5e6cce12ce49b6a922bf6da1fef0e1 |
| 出典メモ | uspto-grants-1986_09 |