化工社化工社 化学情報印刷レポート · 研究参考用
7-Oxodehydroepiandrosterone 3-acetate → 7-Keto-dehydroepiandrosterone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 7-Oxodehydroepiandrosterone 3-acetate | HCID 9798229 | — |
| 溶媒 | Acetone hexane | HCID 21880519 | — |
| 生成物 | 7-Keto-dehydroepiandrosterone | HCID 193313 | — |
反応手順
The last remains of the product (3) from the mother liquor were obtained by column chromatography of the mother liquor (adsorbed on silica gel) on a small column of silica gel (80-200 mesh) utilizing hexane-acetone (85:15) as eluent. An additional 0.15 gm of 7-oxo-DHEA-Ac (3) was obtained. Total yield 1.75 gm, 56.5% (based on 90% conversion), melting point 185-186° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06274746B1 |
| 出典データセット | uspto-grants-2001_08 |
| ORD ID | ord-0d502652bd5e4f399ebf5446d026786f |
| 出典メモ | uspto-grants-2001_08 |