化工社化工社 化学情報印刷レポート · 研究参考用
Trifluoroacetic acid → Ethyl 4-[14-(trimethylsilyl)tetradecylamino]benzoylacetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trifluoroacetic acid | HCID 6422 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | tert-Butyl ethyl 4-[14-(trimethylsilyl)tetradecylamino]benzoylmalonate | HCID 20198261 | — |
| 生成物 | Ethyl 4-[14-(trimethylsilyl)tetradecylamino]benzoylacetate | HCID 20198260 | — |
反応手順
A solution of 3.0 g. of tert-butyl ethyl 4-[14-(trimethylsilyl)tetradecylamino]benzoylmalonate and 10 ml. of trifluoroacetic acid is warmed with stirring for 3 hours. The solution is poured onto ice and neutralized with potassium hydroxide. The resulting precipitate is collected by filtration, washed with water and dried. Recrystallization affords the product as a white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04670421 |
| 出典データセット | uspto-grants-1987_06 |
| ORD ID | ord-72e4124e5c5e4f489fda6adeebfa3568 |
| 出典メモ | uspto-grants-1987_06 |