化工社化工社 化学情報印刷レポート · 研究参考用
2,6-Dichlorobenzoyl chloride → 5-(2,6-Dichlorobenzamido)-3-Trichloromethyl-1,2,4-Thiadiazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,6-Dichlorobenzoyl chloride | HCID 78392 | — |
| 反応物 | 3-(Trichloromethyl)-1,2,4-thiadiazol-5-amine | HCID 602848 | — |
| 溶媒 | 1,4-Dichlorobenzene | HCID 4685 | — |
| 生成物 | 5-(2,6-Dichlorobenzamido)-3-Trichloromethyl-1,2,4-Thiadiazole | HCID 13041523 | 22% |
反応手順
A solution of 22.0 g (0.1 mole) 5-amino-3-trichloromethyl-1,2,4-thiadiazole and 20.1 g (0.1 mole) 2,6-dichlorobenzoyl chloride was refluxed for 8 hours in 200 ml dichlorobenzene. After filtration, the crude product precipitated from the filtrate upon standing. Recrystallization from toluene gave 8.6 g (22% yield) of pure product; m.p. 209° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04343945 |
| 出典データセット | uspto-grants-1982_08 |
| ORD ID | ord-052451e8e991401cb49c193ee700dc5f |
| 出典メモ | uspto-grants-1982_08 |