化工社化工社 化学情報印刷レポート · 研究参考用
1-Methyl-3-phenylthiourea → 4-(4-Chloro-3-sulfamoylphenyl)-3-methyl-2-phenyliminothiazolidin-4-ol hydrobromide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Methyl-3-phenylthiourea | HCID 698294 | — |
| 反応物 | Bromo-4'-chloro-3'-sulfamoylacetophenone | HCID 12952390 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | 4-(4-Chloro-3-sulfamoylphenyl)-3-methyl-2-phenyliminothiazolidin-4-ol hydrobromide | HCID 20527204 | — |
反応手順
A solution of 3.13 g (0.01 mole) of 2-bromo-4'-chloro-3'-sulfamoylacetophenone in 50 ml of acetone is added to a solution of 1.66 g (0.01 mole) of 3-methyl-1-phenylthiourea in 100 ml of acetone, whilst stirring with a magnetic stirrer; during this addition the reaction temperature should not rise above 30° C. After stirring for 5 hours at room temperature, the crystals are filtered off. Melting point 164° C. (with decomposition).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04346088 |
| 出典データセット | uspto-grants-1982_08 |
| ORD ID | ord-26948c1cc814490585fe6a8ee4e52ee8 |
| 出典メモ | uspto-grants-1982_08 |