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N-(1-Cyano-piperidin-4-yl)-N-cyclopropyl-4-oxazol-5-yl-benzamide → N-Cyclopropyl-4-oxazol-5-yl-N-[1-(3-propyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-benzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-(1-Cyano-piperidin-4-yl)-N-cyclopropyl-4-oxazol-5-yl-benzamide | HCID 86678209 | — |
| 反応物 | HCID 178449909 | HCID 178449909 | — |
| 生成物 | N-Cyclopropyl-4-oxazol-5-yl-N-[1-(3-propyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-benzamide | HCID 68351877 | — |
反応手順
The title compound is prepared from N-(1-cyano-piperidin-4-yl)-N-cyclopropyl-4-oxazol-5-yl-benzamide and N-hydroxy-butyramidine following a procedure analogous to that described in Example 1. LC (method 6): tR=1.15 min; Mass spectrum (ESI+): m/z=422 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08822471B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-1f127e7fc3bd4790a96429f062fdc600 |
| 出典メモ | uspto-grants-2014_09 |