化工社化工社 化学情報印刷レポート · 研究参考用
2-Chloro-5-ethylpyrimidine → N-Cyclopropyl-N-[1-(5-ethyl-pyrimidin-2-yl)-3-methyl-piperidin-4-yl]-4-oxazol-5-yl-benzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chloro-5-ethylpyrimidine | HCID 3572763 | — |
| 反応物 | HCID 68290188 | HCID 68290188 | — |
| 溶媒 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 生成物 | N-Cyclopropyl-N-[1-(5-ethyl-pyrimidin-2-yl)-3-methyl-piperidin-4-yl]-4-oxazol-5-yl-benzamide | HCID 68351874 | — |
反応手順
The title compound is prepared from N-cyclopropyl-N-(3-methyl-piperidin-4-yl)-4-oxazol-5-yl-benzamide and 2-chloro-5-ethyl-pyrimidine following a procedure analogous to that described in Example 19 using N-methylpyrrolidinone as solvent. LC (method 3): tR=1.83 min; Mass spectrum (ESI+): m/z=432 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08822471B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-8ff19b4de1b04a52abe88db08cbe8a5c |
| 出典メモ | uspto-grants-2014_09 |