3-Bromo-4-fluoroaniline → HCID 178505101、化合物

関与物質

反応手順

The title compound was prepared according to the procedure of Example 17, step E, using N′-hydroxy-4-({3-[(methylsulfonyl)amino]propyl}amino)-1,2,5-oxadiazole-3-carboximidamide and 3-bromo-4-fluoroaniline [Oakwood Products, Inc., product #013091] as the starting materials in 12% yield. LCMS for C13H17BrFN6O4S (M+H)+: m/z=451.0, 453.0. 1H NMR (400 MHz, CD3OD): δ 7.12 (dd, J=5.9, 2.4 Hz, 1H), 7.05 (t, J=8.7 Hz, 1H), 6.83 (m, 1H), 3.39 (t, J=6.8 Hz, 2H), 3.14 (t, J=6.6 Hz, 2H), 2.94 (s, 3H), 1.87 (m, 2H).

情報源と証拠