化工社化工社 化学情報印刷レポート · 研究参考用
1-Methylcyclopropane-1-sulfonamide → 1-Benzoylcyclopropane-1-sulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Methylcyclopropane-1-sulfonamide | HCID 21889814 | — |
| 反応物 | 1-Benzoyl-N-tert-butylcyclopropane-1-sulfonamide | HCID 21889830 | — |
| 生成物 | 1-Benzoylcyclopropane-1-sulfonamide | HCID 21889794 | 87% |
反応手順
This compound, Example 6,1-benzoylcyclopropyl-sulfonamide, was obtained in 87% yield from N-tert-butyl(1-benzoyl)cyclopropylsul-fonamide using the procedure described for the synthesis of 1-Methylcyclopropylsulfonamide, followed by recrystallization from the minimum amount of EtOAc in hexane: 1H NMR (DMSO-d6) δ 1.39 (m, 2H), 1.61 (m, 2H), 7.22 (s, 2H), 7.53 (t, J=7.6 Hz, 2H), 7.65 (t, J=7.6 Hz, 1H), 8.06 (d, J=8.2 Hz, 2H); 13C NMR (DMSO d6) δ 12.3, 48.4, 128.1, 130.0, 133.4, 135.3, 192.0.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07135462B2 |
| 出典データセット | uspto-grants-2006_11 |
| ORD ID | ord-070a481e14ef4de7bf9500bde3b56a0e |
| 出典メモ | uspto-grants-2006_11 |