化工社化工社 化学情報印刷レポート · 研究参考用
Methyl iodide → Methyl 8-methyl-1,4-dioxaspiro[4.5]decane-8-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl iodide | HCID 6328 | — |
| 反応物 | Lithium diisopropylamide | HCID 2724682 | — |
| 反応物 | Methyl 1,4-dioxaspiro[4.5]decane-8-carboxylate | HCID 10845708 | — |
| 生成物 | Methyl 8-methyl-1,4-dioxaspiro[4.5]decane-8-carboxylate | HCID 22591390 | — |
反応手順
According to the process described in the literature (JP83-118577), methyl 1,4-dioxaspiro [4.5]decan-8-carboxylate was reacted with methyl iodide in the presence of LDA (lithium diisopropylamide) to obtain methyl 8-methyl-1,4-dioxaspiro [4.5]decan-8-carboxylate (the compound (1) of the above figure).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07138397B2 |
| 出典データセット | uspto-grants-2006_11 |
| ORD ID | ord-afc59317940e481da20834cadb4f253c |
| 出典メモ | uspto-grants-2006_11 |