化工社化工社 化学情報印刷レポート · 研究参考用
Vinyltrimethylsilane → 4-Bromo-2-chloro-1-ethenylbenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Vinyltrimethylsilane | HCID 79102 | — |
| 反応物 | 4-Bromo-2-chloro-1-iodobenzene | HCID 2735547 | — |
| 反応物 | 4-Bromo-2-methyl-1-vinylbenzene | HCID 22598656 | — |
| 生成物 | 4-Bromo-2-chloro-1-ethenylbenzene | HCID 57842713 | 96% |
反応手順
Using a procedure analogous to that used to prepare 30A, 4-bromo-2-chloro-1-iodobenzene (8 g, 25 mmol) was reacted with trimethyl(vinyl)silane in a pressure vessel at 160° C. for 1 h and worked up in a manner similar as in 30A to yield 61A (5.2 g, 96%) as an oil. 1H NMR (400 MHz, CDCl3) δ ppm 5.41 (d, J=11.86 Hz, 1 H) 7.02 (dd, J=17.36, 11.21 Hz, 1 H) 7.35 (dd, 1 H) 7.41 (d, 1 H) 7.52 (d, J=1.76 Hz, 1 H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07592331B2 |
| 出典データセット | uspto-grants-2009_09 |
| ORD ID | ord-2d460e143a7a461f97b4fc39ac894499 |
| 出典メモ | uspto-grants-2009_09 |