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1-(2-benzyloxyethyl)-4-[(4-ethylphenyl)methyl]-3-(beta-D-glucopyranosyloxy)-5-methyl-1H-pyrazole → 2-(5-Methyl-pyrazol-1-YL)-ethanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(2-benzyloxyethyl)-4-[(4-ethylphenyl)methyl]-3-(beta-D-glucopyranosyloxy)-5-methyl-1H-pyrazole | HCID 69133733 | — |
| 触媒 | HCID 178418390 | HCID 178418390 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 2-(5-Methyl-pyrazol-1-YL)-ethanol | HCID 12360320 | 372.5% |
反応手順
To a solution of 1-(2-benzyloxyethyl)-4-[(4-ethylphenyl)methyl]-3-(β-D-glucopyranosyloxy)-5-methyl-1H-pyrazole (0.012 g) in ethanol (2 mL) was added a catalytic amount of 10% palladium-carbon powder, and the mixture was stirred at room temperature under a hydrogen atmosphere for 30 minutes. Insoluble materials were removed by filtration, and the solvent was removed under reduced pressure to give 4-[(4-ethylphenyl)methyl]-3-(β-D-glucopyranosyloxy)-1-(2-hydroxyethyl-5-methyl-1H-pyrazole (0.011 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07087579B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-061bca7ca0d24355a6d61c73b9464cfc |
| 出典メモ | uspto-grants-2006_08 |