化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Bromide → 3-[4-(3-Cyclohexyl-ureido)-phenyl]-isoxazole-5-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Bromide | HCID 253877 | — |
| 反応物 | HCID 67354653 | HCID 67354653 | — |
| 生成物 | 3-[4-(3-Cyclohexyl-ureido)-phenyl]-isoxazole-5-carboxylic acid | HCID 67352849 | 92% |
反応手順
The title compound was prepared from 3-[4-(3-cyclohexyl-ureido)-phenyl]-isoxazole-5-carboxylic acid ethyl ester as set forth in Example 8 and was obtained in 92% yield. Mass (ES+): 330 (M++1); IR (KBr): 3318, 2927, 2853, 1711, 1637, 1563; 1H NMR (DMSO-d6) δ: 1.05-1.80 (4×m, 10H), 3.45 (br, 1H), 6.17 (d, 1H), 7.49 (d, 2H), 7.66 (s, 1H), 7.79 (d, 2H), 8.58 (s, 1H), 14.5 (br, ˜0.5H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08835428B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-4dacd620a29e4a369674d3405a3a8192 |
| 出典メモ | uspto-grants-2014_09 |