関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 1-[3-(1-Methyl-1H-benzoimidazol-2-yl)-phenyl]-piperidine-4-carboxylic acid ethyl ester | HCID 66977525 | — |
| 生成物 | HCID 66977624 | HCID 66977624 | — |
反応手順
Method 11—Step b A mixture of 1-[3-(1-Methyl-1H-benzoimidazol-2-yl)-phenyl]-piperidine-4-carboxylic acid ethyl ester (3.10 g, 8.54 mmol) in 6N HCl (25.0 mL) was heated in microwave at 120° C. for 20 minutes. Then solvent was removed to obtain the title compound in quantitative yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08835648B2 |
|---|
| 出典データセット | uspto-grants-2014_09 |
|---|
| ORD ID | ord-3022dd85f3864658a6519426f83a199f |
|---|
| 出典メモ | uspto-grants-2014_09 |
|---|
