関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 2-Chloro-5-chloromethylthiazole | HCID 2763179 | — |
| 反応物 | Piperidin-2-one--hydrogen chloride (1/1) | HCID 20088740 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | 1-(2-Chloro-5-thiazolylmethyl)piperidine 4-one | HCID 70655845 | — |
反応手順
25 gm of piperidone hydrochloride was taken in 250 ml acetonitrile. 68.7 gm of K2CO3 was added under stirring at 60° C., followed by addition of 27.8 gm of 2-chloro-5-chloromethylthiazole and refluxed for 6 hours.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08841296B2 |
|---|
| 出典データセット | uspto-grants-2014_09 |
|---|
| ORD ID | ord-0e71ca6a87394df3ad9714f21e115bdd |
|---|
| 出典メモ | uspto-grants-2014_09 |
|---|
