化工社化工社 化学情報印刷レポート · 研究参考用
(R)-(-)-2-Amino-1-propanol → (2R)-2-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propan-1-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (R)-(-)-2-Amino-1-propanol | HCID 80308 | — |
| 反応物 | (4,6-Dichloropyrimidin-5-yl)acetaldehyde | HCID 13989292 | — |
| 生成物 | (2R)-2-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propan-1-ol | HCID 86672074 | — |
反応手順
The title compound was prepared according to the method described for Preparation 1 using (4,6-dichloropyrimidin-5-yl)acetaldehyde and (R)-2-amino-1-propanol to afford the title compound as a yellow solid in 100% yield, 11.12 g.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08846698B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-724f7da987ad489a87231b8b832ce6de |
| 出典メモ | uspto-grants-2014_09 |