関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | N,N-Dimethylaniline | HCID 949 | — |
| 反応物 | Phthalic Anhydride | HCID 6811 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 溶媒 | Chlorobenzene | HCID 7964 | — |
| 生成物 | 2-[4-(Dimethylamino)benzoyl]benzoic acid | HCID 88937 | — |
反応手順
A mixture of phthalic anhydride (30 g.), N,N-dimethylaniline (60.5 g.), aluminum chloride (60 g.) and chlorobenzene (180 g.) was heated (to 75° C.) during one hour, then cooled. Ice (500 ml.) was added, the chlorobenzene layer was separated and the chlorobenzene was steam distilled. Addition of base to a solution of the residue in dilute sulfuric acid afforded 2-(4-(dimethylamino)benzoyl)benzoic acid (IV: Y2 = Z4 = Z"5 = Z"6 = Z7 = H, Y'4 = (CH3)2N).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04096176 |
|---|
| 出典データセット | uspto-grants-1978_06 |
|---|
| ORD ID | ord-f88fec8b9caf4f29924de010ab035256 |
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| 出典メモ | uspto-grants-1978_06 |
|---|
