Phenol → 1,1,1-Trichloro-2,2-bis(4-hydroxyphenyl)ethane

HRID 840332

反応式

HRID 840332 の反応式
S(=O)(=O)(O)O.[C:6]1([OH:12])[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.O=[CH:14][C:15]([Cl:18])([Cl:17])[Cl:16]>O>[Cl:16][C:15]([Cl:18])([Cl:17])[CH:14]([C:9]1[CH:10]=[CH:11][C:6]([OH:12])=[CH:7][CH:8]=1)[C:9]1[CH:10]=[CH:11][C:6]([OH:12])=[CH:7][CH:8]=1

参加物

5

反応物 3

HCID 996PhenolHCID 1118Sulfuric Acid2 回HCID 6407Chloral

生成物 1

HCID 763021,1,1-Trichloro-2,2-bis(4-hydroxyphenyl)ethane収率 98.2%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A 4-necked 3-L flask, equipped with a mechanical stirrer, a nitrogen inlet, and thermometer, is charged with 83% sulfuric acid (640 g). To this sulfuric acid, phenol (354 g) is added at 20° C. Chloral (200 g) in an additional funnel is added dropwise to the phenolic stirring mixture. The reaction temperature is maintained below 30° C. After the addition, the mixture is allowed to stir at room temperature for 18 hours, before water (640 g) is added. The resulting mixture is filtered and washed with more water to afford 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (423 g) as white solids.

後処理

  1. customA 4-necked 3-L flask, equipped with a mechanical stirrer, a nitrogen inlet
  2. temperatureThe reaction temperature is maintained below 30° C
  3. additionAfter the addition
  4. additionis added
  5. filtrationThe resulting mixture is filtered
  6. washwashed with more water

出典と根拠

ORDレコード
ord-400d79d45a384523bd918e99381092e8
出典データセット
uspto-grants-2002_04
特許番号
US06365671B1

関連ノート

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