化工社化工社 化学情報印刷レポート · 研究参考用
Hydrogen Bromide → HCID 178419246、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrogen Bromide | HCID 260 | — |
| 反応物 | (3-Mercaptopropyl)ammonium chloride | HCID 197870 | — |
| 反応物 | 4-Methylimidazol-5-ylmethanolhydrochloride | HCID 3084707 | — |
| 生成物 | HCID 178419246 | HCID 178419246 | — |
反応手順
A solution of homocysteamine hydrochloride (22.0 g.) and 4-hydroxymethyl-5-methylimidazole hydrochloride (25.6 g.) in aqueous hydrobromic acid (500 ml.) was heated under reflux for one hour. Concentration under reduced pressure, followed by recrystallisation from methanol-isopropyl alcohol afforded 4-methyl-5-[(3-aminopropyl)thiomethyl]-imidazole dihydrobromide (24.5 g.), m.p. 200.5°-202.5°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04293699 |
| 出典データセット | uspto-grants-1981_10 |
| ORD ID | ord-5c03afb5b75a493baa34d35232237405 |
| 出典メモ | uspto-grants-1981_10 |