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Phenethylamine, m-trifluoromethyl- → HCID 69342790、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phenethylamine, m-trifluoromethyl- | HCID 104223 | — |
| 反応物 | Sodium borohydride | HCID 4311764 | — |
| 反応物 | (4-Cyclopropylbenzyl)-[2-(4-fluoro-3-trifluoromethylphenyl)-ethyl]-amine | HCID 69342889 | — |
| 反応物 | 4-(1-Methoxycyclopropyl)-benzaldehyde | HCID 86093727 | — |
| 生成物 | HCID 69342790 | HCID 69342790 | — |
反応手順
The title compound was synthesized in analogy to (4-cyclopropylbenzyl)-[2-(4-fluoro-3-trifluoromethylphenyl)-ethyl]-amine (described in example S53) using 4-(1-methoxy-cyclopropyl)-benzaldehyde (105 mg, 0.60 mmol), 2-(3-trifluoromethylphenyl)-ethylamine (113 mg, 0.60 mmol) and sodium borohydride (34 mg, 0.89 mmol). The desired product was isolated without further purification as a colorless oil. MS (ISP) 350.4 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07259183B2 |
| 出典データセット | uspto-grants-2007_08 |
| ORD ID | ord-265f379c2c0b448885da0caac7c72715 |
| 出典メモ | uspto-grants-2007_08 |