化工社化工社 化学情報印刷レポート · 研究参考用
2-(Piperidin-1-yl)acetic acid hydrochloride → HCID 68358088、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(Piperidin-1-yl)acetic acid hydrochloride | HCID 201096 | — |
| 反応物 | methyl 4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-amino-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)benzoate | HCID 68357865 | — |
| 生成物 | HCID 68358088 | HCID 68358088 | — |
反応手順
The title compound was prepared from methyl 4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-amino-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)benzoate following the general procedure described for the parallel synthesis of C-17 amides above, using piperidin-1-ylacetic acid hydrochloride as the reacting carboxylic acid. LCMS: m/e 655.7 (M+H)+, 4.68 min (method 3).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08846647B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-d8a4c55f5c2b455eba91048c01a0c8fc |
| 出典メモ | uspto-grants-2014_09 |