Melamine → N-(4,6-Diamino-1,3,5-triazin-2-yl)pyridine-3-carboxamide

関与物質

反応手順

4.9 g of melamine and 17 g of nicotinic acid anhydride are refluxed in 300 ml of pyridine with stirring for 3 hours. After cooling, the pyridine is removed by evaporation to dryness under vacuum and the residue is washed with 3% aqueous potassium carbonate and then with water. The residue is fractionated and recrystallized from methanol to yield 2-nicotinamido-4,6-diamino-s-triazine [monomicotinoylmelamine], melting point 252° - 254° C in a yield of 2.4 g and 2,4-bis(nicotinamido)-6-amino-s-triazine [dinicotinoylmelamine], melting point 265° - 270° C (dec) in a yield of 0.15 g.

情報源と証拠